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Search Result

Search Results for " mek 2 "

Targets

MEK MAPK

30

Compounds

1

Natural Products

301

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T6760 APS-2-79 hydrochloride APS-2-79 HCl,APS-2-79 MEK , MAPK
APS-2-79 hydrochloride (APS-2-79 HCl) is a MAPK antagonist that modulating KSR-dependent MAPK signalling by antagonizing RAF heterodimerization as well as the conformational changes required for phosphorylation and activ...
T74361 MEK/PI3K-IN-2
MEK/PI3K-IN-2 (compound 6s), a potent inhibitor of both MEK and PI3K, demonstrates IC50 values of 352 nM (MEK1), 107 nM (PI3Kα), and 137 nM (PI3Kδ). This compound effectively reduces pAKT and pERK1/2 levels, exhibiting a...
T7610 GW284543 UNC10225170 MEK
GW284543 (UNC10225170) is a selective inhibitor of MEK5 .
T9321 Zapnometinib ATR-002,3,4-difluoro-2-(2-chloro-4-iodophenylaMino)-benzoic acid,PD0184264,2-(2-chloro-4-iodoanilino)-3,4-difluorobenzoic acid Influenza Virus , MEK , Antibacterial
Zapnometinib (ATR-002) is a MEK inhibitor.
T6131 Pimasertib AS703026,MSC1936369B,SAR 245509 MEK
Pimasertib (AS703026) is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic activity.
T5857 Trametinib (DMSO solvate) Trametinib DMSO solvate,GSK-1120212 (DMSO solvate),Trametinib dimethyl sulfoxide,JTP-74057 (DMSO solvate) Apoptosis , MEK
Trametinib (DMSO solvate) (GSK-1120212 (DMSO solvate)) is a Highly Potent and Selective MEK Inhibitor that specifically inhibits MEK1/2(IC50 :2 nM)
T6083 AZD8330 ARRY-424704,ARRY-704 ERK , MEK
AZD8330 (ARRY-704) is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with IC50 of 7 nM. Phase 1.
T2623 PD98059 PD 98059 ERK , Aryl Hydrocarbon Receptor , MEK , Autophagy
PD98059 is an MEK inhibitor that inhibits MEK1 and MEK2 (IC50=2/50 μM) and is non-ATP-competitive. PD98059 is also antagonistic as a ligand for AHR. PD98059 inhibits autophagy.
T6189 Mirdametinib PD325901,PD0325901 Apoptosis , MEK , Autophagy
Mirdametinib (PD325901) is an MEK inhibitor (IC50=0.33 nM) with selective, non-ATP-competitive, and oral activity. Mirdametinib exhibits antitumor activity by inhibiting p-ERK1/2 expression and inducing apoptosis.
T6692 TAK-733 TAK733,TAK 733 MEK
TAK-733 is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic activity.
T6419 BMS-536924 HY-10262,BMS 536924,CS-0117 Apoptosis , FAK , MEK , IGF-1R , Src
BMS-536924 (BMS 536924) is an ATP-competitive IGF-1R/IR inhibitor with IC50 of 100 nM/73 nM, modest activity for Mek, Fak, and Lck with very little activity for Akt1, MAPK1/2.
T2508 Binimetinib ARRY-438162,ARRY-162,MEK162 MEK , Autophagy
Binimetinib (ARRY-162) (MEK162, ARRY-162, ARRY-438162) is an orally available inhibitor of MEK1/2 (IC50: 12 nM) in a cell-free assay.
T3623 Cobimetinib RG7420,XL518,GDC-0973 Apoptosis , MEK
Cobimetinib (GDC-0973) is a selective inhibitor of mitogen-activated protein kinase kinase (MEK) (IC50: 0.9 nM). Cobimetinib specifically binds to and inhibits the catalytic activity of MEK1, resulting in inhibition of e...
T2443 CI-1040 PD 184352 Apoptosis , MEK
CI-1040 (PD 184352) (PD184352) is an ATP non-competitive MEK1/2 inhibitor (IC50: 17 nM).
T12697 Refametinib R enantiomer RDEA119 R enantiomer,Refametinib R enantiomer,BAY 869766 R enantiomer MEK
Refametinib R enantiomer (RDEA119 R enantiomer) is an MEK inhibitor with an EC50 of 2.0-15 nM.Refametinib (R enantiomer) has anticancer activity and can be used in cancer research.
T21332 U0126 U 0126,U-0126 Mitophagy , MEK , Autophagy
U0126, an effective and selective non-competitive inhibitor of MAP kinase, inhibits MEK-1 and MEK-2 with IC50 values of 0.07 and 0.06 μM respectively. U0126 inhibits autophagy and mitophagy.
T79048 MEK-IN-6 hydrate MEK
MEK-IN-6 hydrate (compound 69), a MEK inhibitor, exhibits an IC50 value of 2 nM in A375 cells [1].
T23484 U0124 Others
Inactive analog of U0126(MEK-1/2 inhibitor), used as a negative control
T79047 MEK-IN-6 ERK
MEK-IN-6 (Example 69), a potent MEK inhibitor, effectively inhibits ERK1/2 (Thr202/Tyr204) phosphorylation in A375 cells, with an IC50 of 2 nM, making it valuable for cancer research [1].
T74360 MEK/PI3K-IN-1
MEK/PI3K-IN-1 (compound 6r) is a potent inhibitor targeting both MEK and PI3K, exhibiting IC50 values of 124 nM for MEK1, 130 nM for PI3Kα, and 236 nM for PI3Kδ. It effectively reduces levels of pAKT and pERK1/2, demonst...
T40217 PD0325901-O-C2-dioxolane PD0325901-O-C2-dioxolane
PD0325901-O-C2-dioxolane is a chemical compound primarily composed of the MEK inhibitor PD0325901. It can be utilized, in conjunction with either a VHL or CRBN E3 ligase ligand, for the synthesis of MEK1/2 degrader.
T68270 Avutometinib potassium
Avutometinib potassium is a MEK inhibitor (MEKi) that enhanced the inhibition of pseudovirus infection by GLPG-0187. It Blocks SARS-CoV-2 Delta and Omicron Pseudovirus Infection of Airway Epithelial Cells In Vitro, Which...
T70004 APS-2-79
APS-2-79, a KSR-dependent MEK antagonist, disrupts ATP (biotin) binding within the KSR2-MEK1 complex, achieving an inhibitory concentration (IC50) of 120 nM. This action stabilizes the KSR inactive state and antagonizes ...
T68459 RO4927350
RO4927350 is a potent and highly selective non-ATP-competitive MEK1/2 inhibitor. RO4927350 selectively blocks the MAPK pathway signaling both in vitro and in vivo, which results in significant antitumor efficacy in a bro...
T68267 RO5068760
RO5068760 , a substituted hydantoin, is a potent, highly selective, non-adenosine triphosphate (ATP)-competitive MEK1/2 inhibitors. RO5068760 shows significant efficacy in a broad spectrum of tumors with aberrant mitogen...
T71163 Pimasertib HCl
Pimasertib HCl is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic activity. Pimasertib selectively binds to and inhibits the activity of MEK1/2, preventing the acti...
T78608 Anticancer agent 164 Apoptosis
CML-IN-1, also known as compound 7 and compound 4, is a potent anticancer agent that demonstrates a strong induced-apoptosis effect in the human chronic myeloid leukemia (CML) cell line K562. It diminishes protein phosph...
TP2091 Antisauvagine-30
Potent, selective and competitive corticotropin-releasing factor CRF2 receptor antagonist (Kd values are 1.4 and 153.6 nM for binding to mouse CRF2β and rat CRF1 receptors respectively). Inhibits sauvagine-stimulated cAM...
T79143 MS934 MEK
MS934, a novel VHL-recruiting MEK 1/2 degrader, exhibits potent anti-proliferative effects on HT-29 cell growth, achieving a GI50 of 0.023 μM. It holds potential for researching various human cancers including melanoma, ...
T35536 Tpl2 Kinase Inhibitor (hydrochloride)
Tpl2 kinase inhibitor is an inhibitor of tumor progression locus 2 (Tpl2; IC50= 0.05 μM).1It is selective for Tpl2 over MEK, p38 MAPK, Src, MK2, and PKC (IC50s = >40, 180, >400, 110, and >400 μM, respectively). Tpl2 kina...

Compounds

APS-2-79 hydrochloride
T6760
Synonym: APS-2-79 HCl,APS-2-79
Target: MEK, MAPK
MEK/PI3K-IN-2
T74361
Synonym:
Target:
GW284543
T7610
Synonym: UNC10225170
Target: MEK
zapnometinib
T9321
Synonym: ATR-002,3,4-difluoro-2-(2-chloro-4-iodophenylaMino)-benzoic acid,PD0184264,2-(2-chloro-4-iodoanilino)-3,4-difluorobenzoic acid
Target: Influenza Virus, MEK, Antibacterial
Pimasertib
T6131
Synonym: AS703026,MSC1936369B,SAR 245509
Target: MEK
Trametinib (DMSO solvate)
T5857
Synonym: Trametinib DMSO solvate,GSK-1120212 (DMSO solvate),Trametinib dimethyl sulfoxide,JTP-74057 (DMSO solvate)
Target: Apoptosis, MEK
AZD8330
T6083
Synonym: ARRY-424704,ARRY-704
Target: ERK, MEK
PD98059
T2623
Synonym: PD 98059
Target: ERK, Aryl Hydrocarbon Receptor, MEK, Autophagy
Mirdametinib
T6189
Synonym: PD325901,PD0325901
Target: Apoptosis, MEK, Autophagy
TAK-733
T6692
Synonym: TAK733,TAK 733
Target: MEK
BMS-536924
T6419
Synonym: HY-10262,BMS 536924,CS-0117
Target: Apoptosis, FAK, MEK, IGF-1R, Src
Binimetinib
T2508
Synonym: ARRY-438162,ARRY-162,MEK162
Target: MEK, Autophagy
Cobimetinib
T3623
Synonym: RG7420,XL518,GDC-0973
Target: Apoptosis, MEK
CI-1040
T2443
Synonym: PD 184352
Target: Apoptosis, MEK
Refametinib R enantiomer
T12697
Synonym: RDEA119 R enantiomer,Refametinib R enantiomer,BAY 869766 R enantiomer
Target: MEK
U0126
T21332
Synonym: U 0126,U-0126
Target: Mitophagy, MEK, Autophagy
MEK-IN-6 hydrate
T79048
Synonym:
Target: MEK
U0124
T23484
Synonym:
Target: Others
MEK-IN-6
T79047
Synonym:
Target: ERK
MEK/PI3K-IN-1
T74360
Synonym:
Target:
PD0325901-O-C2-dioxolane
T40217
Synonym: PD0325901-O-C2-dioxolane
Target:
Avutometinib potassium
T68270
Synonym:
Target:
APS-2-79
T70004
Synonym:
Target:
RO4927350
T68459
Synonym:
Target:
RO5068760
T68267
Synonym:
Target:
Pimasertib HCl
T71163
Synonym:
Target:
Anticancer agent 164
T78608
Synonym:
Target: Apoptosis
Antisauvagine-30
TP2091
Synonym:
Target:
MS934
T79143
Synonym:
Target: MEK
Tpl2 Kinase Inhibitor (hydrochloride)
T35536
Synonym:
Target:
Cat No. Product Name Synonyms Targets
T6S1740 Nardosinone Others
1. Nardosinone has inhibitory effect on Ang II-induced hypertrophy in H9c2 cells, might be mediated by targeting PI3K/Akt and MEK/ERK signaling pathways. 2. Nardosinone could protect against the neuronal injury exposed t...

Natural Products

Nardosinone
T6S1740
Synonym:
Target: Others

Recombinant Proteins

Species：
Human (252)
Mouse (45)
Bovine (1)
Cynomolgus (1)
Human (1)
Rat (1)
Expression System：
HEK293 (172)
E. coli (70)
Baculovirus-Insect Cells (31)
Human Cells (27)
Yeast (1)
Tag：
His (105)
hFc (36)
Tag Free (26)
C-6His (20)
C-His-Avi (13)
His,GST (13)
GST (10)
None (8)
C-His (7)
His,AVI (7)
Cat No. Product Name Species Expression System
TMPK-00812 Midkine Protein, Mouse, Recombinant (His) Mouse E. coli
Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue hom...
TMPK-00024 Midkine Protein, Human, Recombinant (His & Avi), Biotinylated Human E. coli
Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue hom...
TMPK-00023 Midkine Protein, Human, Recombinant (His & Avi) Human E. coli
Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue hom...
TMPY-04544 MEK2 Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
Dual specificity mitogen-activated protein kinase kinase 2, also known as MAP kinase kinase 2, MAPKK2, ERK activator kinase 2, MAPK / ERK kinase 2, MEK2 and MAP2K2, is a member of the protein kinase superfamily, STE Ser/...
TMPY-05004 FGF-4 Protein, Human, Recombinant Human E. coli
FGF (fibroblast growth factor) signalling is known to be required for many aspects of mesoderm formation and patterning during Xenopus development and has been implicated in regulating genes required for the specificati...
TMPY-04412 Germinal Center Kinase/MAP4K2 Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
Mitogen-activated protein kinase kinase kinase kinase 2, also known as B lymphocyte serine/threonine-protein kinase, Germinal center kinase, MAPK/ERK kinase kinase kinase 2, MEK kinase kinase 2, Rab8-interacting protein,...
TMPY-02519 BLVRB Protein, Human, Recombinant (His) Human E. coli
Biliverdin reductase (hBVR) is a serine/threonine kinase that catalyzes reduction of the heme oxygenase (HO) activity product, biliverdin, to bilirubin. BVR consists of an N-terminal dinucleotide-binding domain (Rossmann...
TMPY-04389 MAP3K8 Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
Mitogen-activated protein kinase kinase kinase 8, also known as Cancer Osaka thyroid oncogene, Proto-oncogene c-Cot, Serine/threonine-protein kinase cot, Tumor progression locus 2 and MAP3K8, is a cytoplasm protein that ...
TMPY-04562 GRK2 Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
G-protein coupled receptor kinase 2 (GRK2), also referred as Adrenergic, beta, receptor kinase 1 (ADRBK1), is a ubiquitous member of the G protein-coupled receptor kinase (GRK) family that appears to play a central, inte...
TMPY-00850 ST2/IL-1 RL1 Protein, Human, Recombinant Human HEK293
IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn...
TMPY-00891 Neuropilin-1 Protein, Human, Recombinant (V179A, hFc) Human HEK293
Neuropilin is a type I transmembrane protein and the molecular mass is 120 kDa. Two homologs, Neuropilin-1 and Neuropilin-2, are identified. The primary structure of Neuropilin-1 and Neuropilin-2 is well conserved and is...
TMPY-00748 Nectin-2 Protein, Human, Recombinant Human HEK293
Cluster of Differentiation 112 (CD112), also known as poliovirus receptor related protein 2 (PVRL2 or PRR2), is a single-pass type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily. CD112 protein a...
TMPY-00005 FGF-8a Protein, Human, Recombinant Human E. coli
In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment...
TMPY-02358 CD98 Protein, Mouse, Recombinant (His) Mouse HEK293
4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr...
TMPY-01691 Clusterin Protein, Human, Recombinant (CLU34, His) Human HEK293
Clusterin, also known as complement-associated protein SP-40, Complement cytolysis inhibitor, Apolipoprotein J, Testosterone-repressed prostate message 2, Aging-associated gene 4 protein, CLU and APOJ, is a secreted prot...
TMPY-02792 GDNF Protein, Human, Recombinant (HEK293) Human HEK293
Glial cell line-derived neurotrophic factor(GDNF) is an important member of the GDNF family of ligands(GFL). The GDNF family of ligands is comprised by four neurotrophic factors: glial cell line-derived neurotrophic fact...
TMPY-05288 PLGF/PGF Protein, Human, Recombinant (aa 19-149) Human E. coli
PLGF/PGF Protein, Human, Recombinant (aa 19-149) is expressed in E. coli.
TMPY-04116 KRAS Protein,Human,Recombinant(G12C & Q61H, His) Human E. coli
K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec...
TMPY-02011 CD96 Protein, Human, Recombinant (His) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-00871 LAYN Protein, Human, Recombinant (hFc) Human HEK293
Layilin recently characterized as a 55 kDa transmembrane protein with homology to C-type lectins, is present in numerous cell lines and tissue extracts. As one of the adaptor proteins, talin mediates the interactions bet...
TMPY-00849 ST2/IL-1 RL1 Protein, Human, Recombinant (hFc) Human HEK293
IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn...
TMPY-00341 FGFR3 Protein, Human, Recombinant (alpha IIIb, His) Human HEK293
FGFR3, also known as CD333, is a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ ...
TMPJ-00850 ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) Mouse Human Cells
ST2, also called IL-1 R4, is an Interleukin-1 receptor family glycoprotein that plays a role in Th2 immune responses. ST2 is expressed on the surface of mast cells, activated Th2 cells, macrophages, and cardiac myocytes....
TMPY-04396 C-ABL/ABL1 Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cy...
TMPY-04356 GSK3B Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
GSK3B is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It Contains 1 protein kinase domain, and is expressed in the testis, thymus, prostate, and ovary and weakly expressed in the lung, ...
TMPY-02971 CLEC10A Protein, Human, Recombinant (hFc) Human HEK293
CLEC10A, also known as the macrophage galactose-type calcium-type lectins (MGLs; CD301) constitute a unique class of C-type lectins because of their specificity for galactose and its structural homologues. MGLs/CD301 is ...
TMPY-02820 SDF-1 Protein, Human, Recombinant (isoform a) Human E. coli
The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f...
TMPY-05586 CD28H/TMIGD2 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
The orthologue of human IGPR-1 is found only in eukaryotes, including primates, the guinea pig, canines, felines, dolphins, bovines, the llama, bats, the common shrew, and horses. Of interest, the IGPR-1 gene is absent i...
TMPY-01199 CD74 Protein, Human, Recombinant (His) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-05427 CD19 Protein, Human, Recombinant (hFc) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-04113 KRAS Protein,Human,Recombinant(G12D & Q61H, His) Human E. coli
K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec...
TMPY-04844 BTN3A1 Protein, Human, Recombinant (His) Human HEK293
BTN3A1 has the structure of a type I receptor of the Ig superfamily and is part of a family of seven BTN receptors encoded by genes in the MHC. BTN molecules are composed of two Ig domains (IgV, IgC2), a single transmemb...
TMPY-01985 CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 cells.
TMPJ-00335 TGFBR2 Protein, Mouse, Recombinant (His) Mouse Human Cells
Transforming growth factor-β (TGF-β) is an essential regulator in the processes of development, cell proliferation, and extracellular matrix deposition. TGF-β regulates cellular processes by binding to three high-affinit...
TMPY-04829 G-CSF Protein, Human, Recombinant Human HEK293
Granulocyte-colony stimulating factor (G-CSF) is a growth factor and an essential cytokine belonging to the CSF family of hormone-like glycoproteins. It is produced by numerous cell types including immune and endothelial...
TMPY-01935 C-Kit Protein, Human, Recombinant (His) Human HEK293
C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the pr...
TMPY-02096 TACI Protein, Human, Recombinant (His) Human HEK293
Tumor necrosis factor receptor superfamily, member 13B (TNFRSF13B) also known as Transmembrane activator and CAML interactor (TACI) and CD267 antigen, is a member of the tumor necrosis factor receptor superfamily. TNFRSF...
TMPY-01359 ST2/IL-1 RL1 Protein, Human, Recombinant (His) Human HEK293
IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn...
TMPY-00751 TrkB Protein, Human, Recombinant (His) Human HEK293
TrkB receptor also known as TrkB tyrosine kinase or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase, receptor, type 2 (NTRK2) is a single transmembrane catalytic receptor with intracellular tyrosine kin...
TMPY-02367 Neuropilin-1 Protein, Human, Recombinant (isoform b, His) Human HEK293
Neuropilin is a type I transmembrane protein and the molecular mass is 120 kDa. Two homologs, Neuropilin-1 and Neuropilin-2, are identified. The primary structure of Neuropilin-1 and Neuropilin-2 is well conserved and is...
TMPY-04644 PDGFB Protein, Human, Recombinant (His) Human Yeast
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionalit...
TMPY-02231 TrkB Protein, Mouse, Recombinant (His) Mouse HEK293
TrkB receptor also known as TrkB tyrosine kinase or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase, receptor, type 2 (NTRK2) is a single transmembrane catalytic receptor with intracellular tyrosine kin...
TMPY-01888 KRAS Protein,Human, Recombinant (Q61H, His) Human E. coli
K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec...
TMPY-03425 Tau Protein, Human, Recombinant (His) Human E. coli
MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are...
TMPY-05414 NKG2D/CD314 Protein, Mouse, Recombinant (hFc) Mouse Baculovirus-Insect Cells
KLRK1 (Killer Cell Lectin Like Receptor K1) is a Protein Coding gene. NKG2D, also known as CD314, is an immune receptor that consists of two disulfide-linked type II transmembrane proteins with short intracellular protei...
TMPY-00747 Nectin-2 Protein, Human, Recombinant (His) Human HEK293
Cluster of Differentiation 112 (CD112), also known as poliovirus receptor related protein 2 (PVRL2 or PRR2), is a single-pass type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily. CD112 protein a...
TMPY-02500 YKL-40/CHI3L1 Protein, Mouse, Recombinant (His) Mouse HEK293
Chitinase-3-like protein 1 (CHI3L1) is a secreted heparin-binding glycoprotein whose expression is associated with vascular smooth muscle cell migration. CHI3L1 is expressed at high levels in postconfluent nodular VSMC c...
TMPY-01442 DMBT1 Protein, Human, Recombinant (His) Human HEK293
Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB d...
TMPY-01871 IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His) Human HEK293
Interleukin 5 receptor, alpha (IL5RA) also known as CD125 (Cluster of Differentiation 125) is a subunit of the Interleukin-5 receptor. IL5RA (CD125) is an interleukin 5 specific subunit of a heterodimeric cytokine recept...
TMPY-06056 KRAS Protein, Human, Recombinant (G12D, His) Human E. coli
K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec...
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Midkine Protein, Mouse, Recombinant (His)
TMPK-00812
Species: Mouse
Expression System: E. coli
Midkine Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00024
Species: Human
Expression System: E. coli
Midkine Protein, Human, Recombinant (His & Avi)
TMPK-00023
Species: Human
Expression System: E. coli
MEK2 Protein, Human, Recombinant (GST)
TMPY-04544
Species: Human
Expression System: Baculovirus-Insect Cells
FGF-4 Protein, Human, Recombinant
TMPY-05004
Species: Human
Expression System: E. coli
Germinal Center Kinase/MAP4K2 Protein, Human, Recombinant (His & GST)
TMPY-04412
Species: Human
Expression System: Baculovirus-Insect Cells
BLVRB Protein, Human, Recombinant (His)
TMPY-02519
Species: Human
Expression System: E. coli
MAP3K8 Protein, Human, Recombinant (GST)
TMPY-04389
Species: Human
Expression System: Baculovirus-Insect Cells
GRK2 Protein, Human, Recombinant (His & GST)
TMPY-04562
Species: Human
Expression System: Baculovirus-Insect Cells
ST2/IL-1 RL1 Protein, Human, Recombinant
TMPY-00850
Species: Human
Expression System: HEK293
Neuropilin-1 Protein, Human, Recombinant (V179A, hFc)
TMPY-00891
Species: Human
Expression System: HEK293
Nectin-2 Protein, Human, Recombinant
TMPY-00748
Species: Human
Expression System: HEK293
FGF-8a Protein, Human, Recombinant
TMPY-00005
Species: Human
Expression System: E. coli
CD98 Protein, Mouse, Recombinant (His)
TMPY-02358
Species: Mouse
Expression System: HEK293
Clusterin Protein, Human, Recombinant (CLU34, His)
TMPY-01691
Species: Human
Expression System: HEK293
GDNF Protein, Human, Recombinant (HEK293)
TMPY-02792
Species: Human
Expression System: HEK293
PLGF/PGF Protein, Human, Recombinant (aa 19-149)
TMPY-05288
Species: Human
Expression System: E. coli
KRAS Protein,Human,Recombinant(G12C & Q61H, His)
TMPY-04116
Species: Human
Expression System: E. coli
CD96 Protein, Human, Recombinant (His)
TMPY-02011
Species: Human
Expression System: HEK293
LAYN Protein, Human, Recombinant (hFc)
TMPY-00871
Species: Human
Expression System: HEK293
ST2/IL-1 RL1 Protein, Human, Recombinant (hFc)
TMPY-00849
Species: Human
Expression System: HEK293
FGFR3 Protein, Human, Recombinant (alpha IIIb, His)
TMPY-00341
Species: Human
Expression System: HEK293
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)
TMPJ-00850
Species: Mouse
Expression System: Human Cells
C-ABL/ABL1 Protein, Human, Recombinant (GST)
TMPY-04396
Species: Human
Expression System: Baculovirus-Insect Cells
GSK3B Protein, Human, Recombinant (His)
TMPY-04356
Species: Human
Expression System: Baculovirus-Insect Cells
CLEC10A Protein, Human, Recombinant (hFc)
TMPY-02971
Species: Human
Expression System: HEK293
SDF-1 Protein, Human, Recombinant (isoform a)
TMPY-02820
Species: Human
Expression System: E. coli
CD28H/TMIGD2 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-05586
Species: Human
Expression System: HEK293
CD74 Protein, Human, Recombinant (His)
TMPY-01199
Species: Human
Expression System: HEK293
CD19 Protein, Human, Recombinant (hFc)
TMPY-05427
Species: Human
Expression System: HEK293
KRAS Protein,Human,Recombinant(G12D & Q61H, His)
TMPY-04113
Species: Human
Expression System: E. coli
BTN3A1 Protein, Human, Recombinant (His)
TMPY-04844
Species: Human
Expression System: HEK293
CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-01985
Species: Human
Expression System: HEK293
TGFBR2 Protein, Mouse, Recombinant (His)
TMPJ-00335
Species: Mouse
Expression System: Human Cells
G-CSF Protein, Human, Recombinant
TMPY-04829
Species: Human
Expression System: HEK293
c-Kit Protein, Human, Recombinant (His)
TMPY-01935
Species: Human
Expression System: HEK293
TACI Protein, Human, Recombinant (His)
TMPY-02096
Species: Human
Expression System: HEK293
ST2/IL-1 RL1 Protein, Human, Recombinant (His)
TMPY-01359
Species: Human
Expression System: HEK293
TrkB Protein, Human, Recombinant (His)
TMPY-00751
Species: Human
Expression System: HEK293
Neuropilin-1 Protein, Human, Recombinant (isoform b, His)
TMPY-02367
Species: Human
Expression System: HEK293
PDGFB Protein, Human, Recombinant (His)
TMPY-04644
Species: Human
Expression System: Yeast
TrkB Protein, Mouse, Recombinant (His)
TMPY-02231
Species: Mouse
Expression System: HEK293
KRAS Protein,Human, Recombinant (Q61H, His)
TMPY-01888
Species: Human
Expression System: E. coli
Tau Protein, Human, Recombinant (His)
TMPY-03425
Species: Human
Expression System: E. coli
NKG2D/CD314 Protein, Mouse, Recombinant (hFc)
TMPY-05414
Species: Mouse
Expression System: Baculovirus-Insect Cells
Nectin-2 Protein, Human, Recombinant (His)
TMPY-00747
Species: Human
Expression System: HEK293
YKL-40/CHI3L1 Protein, Mouse, Recombinant (His)
TMPY-02500
Species: Mouse
Expression System: HEK293
DMBT1 Protein, Human, Recombinant (His)
TMPY-01442
Species: Human
Expression System: HEK293
IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His)
TMPY-01871
Species: Human
Expression System: HEK293
KRAS Protein, Human, Recombinant (G12D, His)
TMPY-06056
Species: Human
Expression System: E. coli
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